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Originally identified by Loren Pickart in human plasma, GHK-Cu has been the subject of extensive cellular biology and biochemical research literature for over five decades, with research contexts examining tissue biology, cellular signaling pathways, copper-binding peptide chemistry, and extracellular matrix research

Recently, it has gained attention for its off-label use in weight loss, providing an alternative for individuals struggling with obesity

* Correspondence: Fan Guo, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

BPC 157 may be more relevant when the focus is localized tissue repair, tendon or ligament recovery, gut support, wound healing, or inflammation control

To view a copy of this license, visit About this article Cite this article Muoz, J.F., McEwen, J.G., Clay, O.K